Sofia Toniolo

Oct 16, 2024 | alz-journals.onlinelibrary.wiley.com | Bahaaeddin Attaallah |Sofia Toniolo |Maria Raquel Maio |Masud Husain

1 INTRODUCTION Apathy (ie, diminished goal-directed behavior) is a prominent feature in several neurodegenerative disorders, including Alzheimer's disease (AD), Parkinson's disease (PD), and small vessel disease (SVD).1 It burdens patients and caregivers and is a marker of disease progression in some disorders.2, 3 In AD, up to 80% of patients develop apathy, even at early stages, making it a valuable preclinical marker.4 However, it remains poorly understood in AD, with limited behavioral...

Jul 10, 2024 | medrxiv.org | Xin You Tai |Sofia Toniolo |David Llewellyn |Cornelia van Duijn

The authors have declared no competing interest. This work was funded by the Wellcome Trust (Wellcome Trust PhD clinical fellowship to XYT and Wellcome Trust Principal Research Fellowship to MH [206330/Z/17/Z]) and MRC (Clinician Scientist Fellowship to S.M. [MR/P00878/X]) and by the Oxford NIHR Biomedical Research Centre. I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained.

Aug 30, 2023 | cell.com | Sofia Toniolo |Adam Hampshire

HighlightsEven months after recovery from COVID-19 infection, some people continue to experience neurological, psychiatric, and cognitive effects. Recent extensive research using electronic health records, cognitive testing, and neuroimaging has started to clarify the nature of some of these symptoms. COVID-19 offers an unprecedented opportunity to follow individuals from acute infection through to the emergence of post-viral illness on a broad scale.