Soumya Kundu

2 months ago | biorxiv.org | Andrew R. Marderstein |Soumya Kundu |Evin M. Padhi |Salil Deshpande

AbstractWhole genome sequencing has identified over a billion non-coding variants in humans, while GWAS has revealed the non-coding genome as a significant contributor to disease. However, prioritizing causal common and rare non-coding variants in human disease, and understanding how selective pressures have shaped the non-coding genome, remains a significant challenge.