Stephen G. Waxman

May 7, 2024 | nature.com | Zeal Jinwala |Emily E. Hartwell |Mirko Pavicic |Kyle Sullivan |Ke Xu |Daniel Jacobson | +5 more

Correction to: Nature Medicine https://doi.org/10.1038/s41591-024-02839-5, published online 1 March 2024In the version of the article initially published, the pipeline for the cross-ancestry meta-analysis did not accurately code some SNPs such that they were not combined despite being the same polymorphism. To fix this, we correctly annotated the rsIDs for the summary statistics from each ancestry and meta-analyzed them based on the unique rsID for each polymorphism.

Mar 1, 2024 | nature.com | Zeal Jinwala |Emily E. Hartwell |Mirko Pavicic |Kyle Sullivan |Ke Xu |Daniel Jacobson | +5 more

AbstractChronic pain is a common problem, with more than one-fifth of adult Americans reporting pain daily or on most days. It adversely affects the quality of life and imposes substantial personal and economic costs. Efforts to treat chronic pain using opioids had a central role in precipitating the opioid crisis.

Aug 2, 2023 | nejm.org | Stephen G. Waxman |Elizabeth G. Phimister

August 3, 2023N Engl J Med 2023; 389:466-469 DOI: 10.1056/NEJMe2305708Elizabeth G. Phimister, Ph.D., Editor This editorial describes the science behind clinical trials of an inhibitor of the sodium channel NaV1.8 to treat acute postoperative pain. Funding and Disclosures Disclosure forms provided by the author are available with the full text of this editorial at NEJM.org.