Stephen W. Hartley

Jun 13, 2024 | nature.com | Lindsay Morton |Olivia Lee |Stephen W. Hartley |Sara Schonfeld |Elizabeth K Cahoon |Vladimir Drozdovitch | +6 more

AbstractChildhood radioactive iodine exposure from the Chornobyl accident increased papillary thyroid carcinoma (PTC) risk. While cervical lymph node metastases (cLNM) are well-recognized in pediatric PTC, the PTC metastatic process and potential radiation association are poorly understood. Here, we analyze cLNM occurrence among 428 PTC with genomic landscape analyses and known drivers (131I-exposed = 349, unexposed = 79; mean age = 27.9 years).

Mar 7, 2024 | nature.com | Todd Gibson |Stephen W. Hartley |Wendy M. Leisenring |Lucie Turcotte |Stephen J. Chanock

AbstractSurvivors of childhood cancer are at increased risk for subsequent cancers attributable to the late effects of radiotherapy and other treatment exposures; thus, further understanding of the impact of genetic predisposition on risk is needed.