Steven De Jonghe

Nov 25, 2024 | sciencedirect.com | J. Baselga |Nitha Panikkassery Ravi |Steven De Jonghe |Jie Wu

AKT is a Ser/Thr kinase that is highly conserved within the PI3K/AKT pathway. Its functions in cancer cells encompass proliferation, promotion of metabolism, resistance to apoptosis, and maintenance of oxidative homeostasis [1], [2], [3], [4], [5]. The dysfunction of this kinase plays a significant role in the advancement of different types of tumors, including TNBC [6].