Steven K. Higginbottom

2 months ago | cell.com | Anthony L. Shiver |Jiawei Sun |Rebecca N. Culver |Arvie Violette |Char Wynter |Marta Nieckarz | +25 more

1Department of Bioengineering, Stanford University, Stanford, CA 94305, USA 2Department of Genetics, Stanford University, Stanford, CA 94305, USA 3Department of Molecular Biology and Laboratory for Molecular Infection Medicine Sweden (MIMS), Umeå Centre for Microbial Research (UCMR), Science for Life Laboratory (SciLifeLab), Umeå University, Umeå 90187, Sweden 4Department of Veterinary and Biomedical Sciences, South Dakota State University, Brookings, SD 57007, USA 5College of Mathematics and...

Oct 31, 2023 | cell.com | Byrne D.P |Rebecca Gellman |Matthew R Olm |Steven K. Higginbottom

Highlights•Bacteroides and Prevotella sp. are isolated, sequenced from Hadza fecal samples•Bacteroides sp. encode more mucus degrading capacity than Prevotella sp. •Unlike Bacteroides, Prevotella colonization requires dietary plant fiber•Bacteroides outcompetes Prevotella in vivo on low plant fiber dietSummaryIndustrialization has transformed the gut microbiota, reducing the prevalence of Prevotella relative to Bacteroides.