Steven K. Higginbottom

Oct 31, 2023 | cell.com | Byrne D.P |Rebecca Gellman |Matthew R Olm |Steven K. Higginbottom

Highlights•Bacteroides and Prevotella sp. are isolated, sequenced from Hadza fecal samples•Bacteroides sp. encode more mucus degrading capacity than Prevotella sp. •Unlike Bacteroides, Prevotella colonization requires dietary plant fiber•Bacteroides outcompetes Prevotella in vivo on low plant fiber dietSummaryIndustrialization has transformed the gut microbiota, reducing the prevalence of Prevotella relative to Bacteroides.