Matthew R Olm

Feb 28, 2024 | amu.hal.science | Rebecca Gellman |Matthew R Olm |Nicolas Terrapon |Fatima Enam

Hadza Prevotella require diet-derived microbiota-accessible carbohydrates to persist in mice Fichier principal PIIS2211124723012457.pdf (4.35 Mo) Télécharger le fichier Origine : Fichiers éditeurs autorisés sur une archive ouverte Licence : CC BY NC ND - Paternité - Pas d'utilisation commerciale - Pas de modification

Nov 21, 2023 | biorxiv.org | Matthew R Olm |Sean Paul Spencer |Justin L. Sonnenburg |Evelyn Lemus Silva

AbstractIgA, the most highly produced human antibody, is continually secreted into the gut to shape the intestinal microbiota. Methodological limitations have critically hindered defining which microbial strains are targeted by IgA and why. Here, we develop a new technique, Metagenomic Immunoglobulin Sequencing (MIG-Seq), and use it to determine IgA coating levels for thousands of gut microbiome strains in healthy humans.

Oct 31, 2023 | cell.com | Byrne D.P |Rebecca Gellman |Matthew R Olm |Steven K. Higginbottom

Highlights•Bacteroides and Prevotella sp. are isolated, sequenced from Hadza fecal samples•Bacteroides sp. encode more mucus degrading capacity than Prevotella sp. •Unlike Bacteroides, Prevotella colonization requires dietary plant fiber•Bacteroides outcompetes Prevotella in vivo on low plant fiber dietSummaryIndustrialization has transformed the gut microbiota, reducing the prevalence of Prevotella relative to Bacteroides.

Mar 9, 2023 | biorxiv.org | Rebecca Gellman |Matthew R Olm |Nicolas Terrapon |Fatima Enam

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