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3 weeks ago | 
onlinelibrary.wiley.com | Tao Zhu |Boyang Xue |Hui Li |ZhangJun Wang
Conflicts of Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. References 1, , , et al., “Overriding Water Table Control on Managed Peatland Greenhouse Gas Emissions,” Nature 593 (2021): 548–552. 2, , , et al., “Expert Assessment of Future Vulnerability of the Global Peatland Carbon Sink,” Nature Climate Change 11 (2021): 70–77.
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2 months ago | 
nature.com | Shu Chen |Basappa Basappa |Tao Zhu |Vijay Pandey
AbstractTumor dormancy is a substantial clinical obstacle in treatment of estrogen receptor positive mammary carcinoma (ER+MC), contributing to drug resistance, metastatic outgrowth, relapse, and consequent mortality. Preclinical models mimicking clinical anti-estrogen-induced ER+MC dormancy were generated in vivo. Function and a mechanism-based combination treatment were determined in the generated dormancy-like models in vitro, ex vivo, and in vivo.
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Dec 9, 2024 | 
nature.com | Shuwei Zhang |Xi Zhang |Basappa Basappa |Tao Zhu |Vijay Pandey
AbstractIntrinsic and acquired resistance represent major obstacles to optimize outcomes in epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) targeted therapy in lung adenocarcinoma (LUAD). Hence, a deeper understanding of EGFR-TKI resistance mechanisms in LUAD will potentially assist in formulating strategies to delay or overcome such resistance. Herein, it was observed that trefoil factor 3 (TFF3) is a crucial mediator of the LUAD EGFR-TKI response.
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Dec 3, 2024 | 
panewslab.com | Jesse Coghlan |Tao Zhu
Author: Jesse Coghlan, CoinTelegraph; Translated by: Tao Zhu, Golden Finance MicroStrategy Chairman and Bitcoin bullish Saylor told Microsoft's board of directors that if Microsoft went all-in on Bitcoin, the company's market value could increase by nearly $5 trillion. Saylor made the argument in 44 slides in just over three minutes as he presented to Microsoft’s board of directors why the tech giant should buy Bitcoin.
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Nov 10, 2024 | 
mdpi.com | Ying Zhang |Tao Zhu |Wei Zhao |Xinkang Bo
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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Nov 7, 2024 | 
pubs.acs.org | Tao Zhu |Chunhe Li |Xiakun Chu |Eileen E. M
Precise spatiotemporal regulation of gene expression patterns is governed by DNA regulatory elements, particularly enhancers. (1−4) Enhancers can initiate transcription by activating target gene promoters, which are often located thousands to millions of base pairs away. (5,6) It is well established that these distantly separated enhancers and promoters in the 1D genomic sequence must come into close proximity in 3D nuclear space for gene expression.
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Oct 18, 2024 | 
dialnet.unirioja.es | Feng Huang |Tao Zhu |Zhihao Qu |Xiaoye Gao
Ayuda Buscar en la ayuda Buscar en la ayuda The effect of joint inclination angle on mechanical properties of rock mass studied by model test and DEM simulation Feng Huang [1] ; Tao Zhu [1] ; Zhihao Qu [2] ; Xiaoye Gao [2] ; Aichen Zheng [1] [1] State Key Laboratory of Mountain Bridge and Tunnel Engineering, Chongqing Jiaotong University, Chongqing, China [2] School of Civil Engineering, Chongqing Jiaotong University, Chongqing, China Localización: Mechanics based design of structures and...
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Oct 17, 2024 | 
biorxiv.org | Yanyan Liu |Tao Zhu |Xinkai Zhou
AbstractThe integration, through hybridization, of the DD genome into domesticated tetraploid wheat gave rise to allohexaploid wheat, the most cultivated wheat globally growing across diverse environmental conditions. However, the regulatory basis of this integration on increased environmental adaptability in allohexaploid remains largely unexplored.
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Oct 16, 2024 | 
biorxiv.org | Yongli Zhu |Tao Zhu |Lili Nan |Heiyuen Ngan
AbstractCharacterizing the noncoding regions of the genome, particularly the cis-regulatory elements (CREs) located in accessible chromatin regions (ACRs) in gene promoters, is crucial for understanding how gene expression is regulated and how genotype contributes to phenotypic diversity in plants.In this study, we used ATAC-seq to resequence and map the ACRs of 214 maize inbred lines.
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Oct 13, 2024 | 
4spepublications.onlinelibrary.wiley.com | Yining Wang |Dongdong Chen |Shoune Xiao |Tao Zhu
REFERENCES 1, , , et al. Axial crushing response of carbon/glass hybrid composite tubes: an experimental and multi-scale computational study. Compos Struct. 2022; 294:115640. doi:10.1016/j.compstruct.2022.115640 2, , , . Experimental and numerical study of hat shaped CFRP structures under quasi-static axial crushing. Compos Struct. 2020; 249:112465. doi:10.1016/j.compstruct.2020.112465 3, , . Carbon-glass reinforced epoxy hybrid composites for crashworthy structural applications. Polym Compos.
