Ted Schwaba

Jan 14, 2024 | nature.com | Ted Schwaba |K. Paige Harden |Michel G. Nivard

AbstractLatent factors, such as general intelligence, depression and risk tolerance, are invoked in nearly all social science research where a construct is measured via aggregation of symptoms, question responses or other measurements. Because latent factors cannot be directly observed, they are inferred by fitting a specific model to empirical patterns of correlations among measured variables.

Jun 5, 2023 | medrxiv.org | Ted Schwaba |Travis T. Mallard |Adam X. Maihofer |Mijke Rhemtulla

AbstractDifferences in the patterning of genetic sharing and differentiation between groups may arise from differences in biological pathways, social mechanisms, phenotyping and ascertainment. We expand the Genomic Structural Equation Modeling framework to allow for testing Genomic Structural Invariance (GSI): the formal comparison of multivariate genetic architecture across groups of individuals.