Thomas Fanshawe

Sep 14, 2023 | paperity.org | Brian Nicholson |Philip Turner |Thomas Fanshawe |Alice Williams

PLOS ONE, Jul 2023 Background and objective Point-of-care lateral flow device antigen testing has been used extensively to identify individuals with active SARS-CoV-2 infection in the community. This study aimed to evaluate the diagnostic accuracy of two point-of-care tests (POCTs) for SARS-CoV-2 in routine community care.

Jul 21, 2023 | journals.plos.org | Brian Nicholson |Philip Turner |Thomas Fanshawe |Alice Williams

Diagnostic accuracy (primary outcome)The prevalence of SARS-CoV-2 positive RT-PCR tests among participants included in the primary analysis was 39.2% (260/663, 95% CI 35.5% to 43.0%). The SD Biosensor POCT had a sensitivity of 84.0% (178/212, 95% CI 78.3% to 88.6%) and specificity of 98.5% (328/333, 96.5% to 99.5%), and the BD Veritor POCT had a sensitivity of 76.5% (127/166, 69.3% to 82.7%) and specificity of 98.8% (249/252, 96.6% to 99.8%) (Table 2 and S1 Table 1 in S1 File).