Thomas Macdonald

2 months ago | mtlblog.com | Al Sciola |Sofia Misenheimer |Mike Chaar |Thomas Edward MacDonald |Thomas Macdonald

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Jan 3, 2025 | tandfonline.com | Thomas Edward MacDonald |Thomas Macdonald

ABSTRACTNuclear-armed states have sought to secure their nuclear arsenals from preemptive attack by deploying mobile ground-launched missiles. However, recent developments in remote-sensing technologies have spurred a debate about the survivability of ground-mobile missiles. Current scholarship implicitly assumes that mobile missiles will be operated sub-optimally, underestimating the difficulty of tracking mobile missiles and hence their survivability.

Nov 5, 2024 | nature.com | Tanya J. Major |Riku Takei |Yuya Shirai |Wei Qing Wang |Murray Cadzow |Amanda Phipps-Green | +35 more

Correction to: Nature Genetics https://doi.org/10.1038/s41588-024-01921-5. Published online 15 October 2024. In the version of the article originally published, there were errors in the consortium lists at the end of the paper. Maureen Rischmueller, Hyon K. Choi, Masahiro Nakatochi, Jeff N. Miner, Daniel H. Solomon, Kathleen M. Giacomini and Deanna J. Brackman were erroneously listed as members of the Japan Gout Genomics Consortium.

Oct 24, 2024 | mtlblog.com | Mike Chaar |Thomas Edward MacDonald |Thomas Macdonald

I have read and agree to Milla's Terms of Use and Privacy Policy . FreeGain access to free articlesDaily free newsletter(s)Ability to comment on most articlesBuild your 3D avatar and gain pointsEverything in the Free planAd-free reading and browsingUnlimited access to all content including AI summaries Directly support our local and national reporting and become a Patron Cancel anytime. Please enter your email and we'll send you a new password request code.

Oct 15, 2024 | nature.com | Tanya J. Major |Riku Takei |Yuya Shirai |Wei Qing Wang |Murray Cadzow |Amanda Phipps-Green | +35 more

AbstractGout is a chronic disease that is caused by an innate immune response to deposited monosodium urate crystals in the setting of hyperuricemia. Here, we provide insights into the molecular mechanism of the poorly understood inflammatory component of gout from a genome-wide association study (GWAS) of 2.6 million people, including 120,295 people with prevalent gout. We detected 377 loci and 410 genetically independent signals (149 previously unreported loci in urate and gout).