Tianyi Hou

Jan 15, 2024 | onlinelibrary.wiley.com | Tianyi Hou |Lei Chen

CONFLICT OF INTEREST STATEMENT The author declares no conflicts of interest. Supporting Information Filename Description bies202300151-sup-0001-TableS1.docx17.8 KB Supplemental Information. REFERENCES 1 (2006). KATP channels as molecular sensors of cellular metabolism. Nature, 440(7083), 470–476. https://doi.org/10.1038/nature04711 2 (2006). K(ATP) channels and insulin secretion: A key role in health and disease. Biochemical Society Transactions, 34(Pt 2), 243–246.

Dec 6, 2023 | biorxiv.org | Tianyi Hou |Xinjie Mao |Jie Zhang |Miner Deng

AbstractCryptosporidium hominis and Cryptosporidium parvum are major causes of severe diarrhea in humans. Comparative studies of them are hampered by the lack of effective cultivation and cryopreservation methods, especially for C. hominis. Here, we described adapted murine enteroids for the cultivation of one C. parvum IId subtype and nonhuman primate-adapted C. hominis Ib, Im, and In subtypes, which allowed the complete development of the pathogens, producing oocysts infectious to mice.