Timothy R. Blosser

Oct 30, 2024 | nature.com | Johanna Klughammer |Daniel L. Abravanel |Timothy R. Blosser |Yury Goltsev |Chiara Caraccio |Nicole Cullen | +7 more

AbstractAlthough metastatic disease is the leading cause of cancer-related deaths, its tumor microenvironment remains poorly characterized due to technical and biospecimen limitations. In this study, we assembled a multi-modal spatial and cellular map of 67 tumor biopsies from 60 patients with metastatic breast cancer across diverse clinicopathological features and nine anatomic sites with detailed clinical annotations.