Tom Weber

1 month ago | cell.com | Tom Weber |Christine Biben |Denise Miles |Stefan Glaser |Sara Tomei |Cheng-Yu Lin | +6 more

Keywordsclonalbarcodingepiblastphylogeneticspedigreelineage tracingCreembryogenesiscell fatemathematical modelingGet full text accessLog in, subscribe or purchase for full access. References1. Lawson, K.A. ∙ Meneses, J.J. ∙ Pedersen, R.A.Clonal analysis of epiblast fate during germ layer formation in the mouse embryoDevelopment. 1991; 113:891-9112. Tam, P.P. ∙ Behringer, R.R.Mouse gastrulation: the formation of a mammalian body planMech. Dev. 1997; 68:3-253. Thomas, P. ∙ Beddington, R.

Aug 1, 2024 | cell.com | Olivia Stonehouse |Christine Biben |Tom Weber |Alexandra L. Garnham

Highlights•Functional equivalents of adult stem/progenitor cells exist in the fetal liver•Large numbers of bona fide LT-RUs reside in the fetal ST-HSC population•Flt3-cre tracking indicated that multiple LT-RU-forming pathways existSummaryIt has been proposed that adult hematopoiesis is sustained by multipotent progenitors (MPPs) specified during embryogenesis.