Tomoko Nakanishi

Feb 20, 2023 | nature.com | Satoshi Yoshiji |Guillaume Butler-Laporte |Tianyuan Lu |Chen-Yang Su |Tomoko Nakanishi |David Morrison | +5 more

AbstractObesity is a major risk factor for Coronavirus disease (COVID-19) severity; however, the mechanisms underlying this relationship are not fully understood. As obesity influences the plasma proteome, we sought to identify circulating proteins mediating the effects of obesity on COVID-19 severity in humans. Here, we screened 4,907 plasma proteins to identify proteins influenced by body mass index using Mendelian randomization.