Tristan L. Lim

Jan 2, 2025 | openjaw.com | Tristan L. Lim

Content Producer/Videographer Meet Tristan, the video virtuoso of Open Jaw. With a camera in hand and a sense of wanderlust in the heart, Tristan accompanies Nina in many reel adventures around the globe, one shot at a time. Being quite new to OJ, he is still improving on his ability to keep lipstick off of Nina's teeth before hitting record!

Nov 26, 2024 | nature.com | Zhaojun Zhang |Divij Mathew |Tristan L. Lim |Kaishu Mason |Sijia Huang |E. John Wherry | +5 more

Data integration to align cells across batches has become a cornerstone of single-cell data analysis, critically affecting downstream results. Currently, there are no guidelines for when the biological differences between samples are separable from batch effects. Here we show that current paradigms for single-cell data integration remove biologically meaningful variation and introduce distortion. We present a statistical model and computationally scalable algorithm, CellANOVA (cell state space analysis of variance), that harnesses experimental design to explicitly recover biological signals that are erased during single-cell data integration. CellANOVA uses a ‘pool-of-controls’ design concept, applicable across diverse settings, to separate unwanted variation from biological variation of interest and allow the recovery of subtle biological signals. We apply CellANOVA to diverse contexts and validate the recovered biological signals by orthogonal assays. In particular, we show that CellANOVA is effective in the challenging case of single-cell and single-nucleus data integration, where it recovers subtle biological signals that can be validated and replicated by external data. A statistical framework quantifies single-cell batch variation and recovers meaningful biological signals.

Apr 8, 2024 | openjaw.com | Tristan L. Lim

Unique Vacations Inc., an affiliate of the worldwide representatives of Sandals Resorts and Beaches Resorts, announces two new travel advisor booking incentives designed to put some extra cash in their pockets and reward them with a trip to the brand-new Sandals Saint Vincent and the Grenadines, which opened its doors on 27MAR.  During April, travel advisors can earn an extra 1% bonus commission on all new bookings made with Unique Vacations Inc.

Apr 8, 2024 | openjaw.com | Jim Byers |Tristan L. Lim

Brad Warren, Canada Jetlines' Chief Operating Officer (COO), will leave the Company at the end of April 2024 to pursue another opportunity in the industry. Warren joined Canada Jetlines in April 2021 as VP of Maintenance and was promoted to COO in the summer of 2022.

Apr 8, 2024 | openjaw.com | Jim Byers |Tristan L. Lim

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