Turku Brain

Jun 5, 2024 | academic.oup.com | Turku Brain |Clinical Neurosciences

In 1928, Yakovlev1 published an influential case series of individuals with epilepsy who developed parkinsonism. Yakovlev proposed that the neuroanatomical damage associated with lifelong seizures may increase the risk of parkinsonism, suggesting shared pathophysiology. In contrast, Yakovlev also noted that in these cases, seizures decreased or even vanished after the onset of parkinsonism, proposing that the neuroanatomical damage associated with parkinsonism may protect against seizures.

Feb 22, 2024 | karger.com | Clinical Neurosciences |Turku Brain

Keywords: Painful legs and moving toes, Brain stimulation, Repetitive transcranial magnetic stimulation Painful legs and moving toes (PLMT) is a rare debilitating neurological syndrome, characterized by neuropathic pain and involuntary movement in the lower limbs, originally described in 1971 [1]. The neurobiological mechanisms are not yet understood, and there are no published treatment trials.

Jul 3, 2023 | jamanetwork.com | Turku Brain |Clinical Neurosciences |Alexander Cohen |Christopher Lin

Key PointsQuestion  Does lesion-related epilepsy map to a brain network? Findings  In this case-control study of lesion locations in patients who either developed epilepsy or did not, lesions associated with epilepsy occurred in multiple heterogenous brain locations.