Univ. Bordeaux

Nov 3, 2024 | link.springer.com | Institut Origines |Aix-Marseille Université |Univ. Bordeaux |Observatoire de Paris

AbstractObservations of the Jovian upper atmosphere at high latitudes in the UV, IR and mm/sub-mm all indicate that the chemical distributions and thermal structure are broadly influenced by auroral particle precipitations. Mid-IR and UV observations have shown that several light hydrocarbons (up to 6 carbon atoms) have altered abundances near Jupiter’s main auroral ovals.

Jul 16, 2024 | academic.oup.com | Université Paris-Est |Faculté de Médecine |Univ. Bordeaux |Inria Sistm

The EBL2001 phase 2 trial tested the two-dose Ad26.ZEBOV, MVA-BN-Filo Ebola vaccine in Europe. Safety and humoral immunogenicity assessments led to EU market authorization in 2020. Complementary analyses of immune responses are warranted to better characterize vaccine effects. We conducted an ancillary study to analyze changes in the serum and cellular responses. Serum biomarkers of activation/inflammation were evaluated using a Luminex assay.

Jun 7, 2024 | onlinelibrary.wiley.com | Laura Payton |Univ. Bordeaux |Bordeaux INP |Kim Last

1 INTRODUCTION The annual rotation of the Earth around the Sun is the cause of periodic, predictable changes in risks and opportunities for living organisms. Thus, numerous species have evolved annual rhythms (Denlinger, 2022a; Helm & Lincoln, 2017; Ikegami & Yoshimura, 2017) conceptualized mechanistically by the endogenous circannual clock, synchronized by reliable external cues. This clock enables organisms to anticipate seasonal events and initiate biological processes accordingly.

Jun 2, 2024 | link.springer.com | Univ. Bordeaux

AbstractThe role of potentially inappropriate medications (PIMs) in mortality has been studied among those 65 years or older. While middle-aged individuals are believed to be less susceptible to the harms of polypharmacy, PIMs have not been as carefully studied in this group. To estimate PIM-associated risk of mortality and evaluate the extent PIMs explain associations between polypharmacy and mortality in middle-aged patients, overall and by sex and race/ethnicity. Observational cohort study.

May 22, 2024 | diabetesjournals.org | Univ. Bordeaux |Bordeaux INP

Inducible pluripotent stem cell–derived human β-like cells (BLCs) hold promise for both therapy and disease modeling, but their generation remains challenging and their functional analyses beyond transcriptomic and morphological assessments remain limited.