Uxue Uria

Jun 13, 2024 | pubs.rsc.org | Efraim Reyes |Uxue Uria |Liher Prieto |Luisa Carrillo

Organocatalysis as Enabling Tool for Enantioselective Ring-Opening Reactions of Cyclopropanes The rich reactivity profile of cyclopropanes has been extensively explored to trigger new organic transformations that enable unusual disconnective approaches to synthesize molecular motifs that are not easily reached through conventional reactions.

Nov 27, 2023 | onlinelibrary.wiley.com | Manuel Pedrón |Laura Villar |Uxue Uria |Liher Prieto

Introduction Cycloaddition reactions represent one of the most efficient and direct approach for the synthesis of cyclic molecules.1 This type of transformations not only enable the direct construction of the cyclic target in a single step through the reaction between two components involving the consecutive formation of at least two new C−C or C-heteroatom bonds, but also allow for an exquisite degree of selectivity when generating complex molecular scaffolds with multiple stereogenic...

Jul 11, 2023 | mdpi.com | Efraim Reyes |Liher Prieto |Uxue Uria |Luisa Carrillo

Abstract:Asymmetric enamine base activation of carbonyl compounds is a well-known and widely used strategy for providing functionalization of organic compounds in an efficient way. The use of solely organic substances, which in most cases are commercially available primary or secondary amines that are easy to obtain, avoids the use of hazardous substances or metal traces, making this type of catalysis a highly convenient methodology from a sustainable point of view.