Vincent Rajkumar

3 weeks ago | nature.com | Nicholas Boddicker |Thomas M Habermann |Andrew Feldman |Rebecca King |Stephen Ansell |Angela Dispenzieri | +9 more

AbstractWe investigated the prevalence of rare inherited pathogenic variants (PV) in 19 cancer predisposition genes regularly included on multi-gene panel testing based on NCCN guidelines and their association with the risk of lymphoid malignancies (LM) overall and by common lymphoma subtypes and multiple myeloma. The study population included newly diagnosed LM cases (N = 6990) and unrelated controls (N = 42,632), excluding individuals with a history of hematologic malignancy.

Aug 28, 2024 | nature.com | Saurabh Zanwar |Jonas Paludo |Ronald S. Go |Joselle M. Cook |Sikander Ailawadhi |Thomas M Habermann | +10 more

An under-recognized source of bleeding in Waldenström macroglobulinemia (WM) is the development of an acquired von Willebrand syndrome (AVWS) [1]. In WM, the von Willebrand Factor (vWF) glycoprotein can be degraded due to autoantibody destruction, increased shear stress due to hyperviscosity, or sequestered due to adsorption onto malignant cells, leading to the development of AVWS (AVWS-WM) [1, 2].

Jul 8, 2024 | oncodaily.com | Vincent Rajkumar

Vincent Rajkumar shared on X:“2024 update on multiple myeloma is available open access!Latest ASCO24 data. Treatment algorithms. Approach to newly diagnosed myeloma. Approach to Relapsed Myeloma. Update on Immunotherapy for myeloma. All the essentials of myeloma in one paper. Includes diagnostic criteria, risk stratification, prognosis, supportive care, and recommended real world dosing schedules for commonly used regimens.

Dec 15, 2023 | mayoclinicproceedings.org | Hagop Kantarjian |Amir T. Fathi |Vincent Rajkumar

Perspectives and controversies | Innovation in Medicine and SurgeryVolume 99, Issue 1p15-21 aDepartment of Leukemia, The University of Texas MD Anderson Cancer Center, Houston bSection of Hematology, Department of Internal Medicine, Yale University School of Medicine and Yale Comprehensive Cancer, New Haven, CT cLeukemia Program, Massachusetts General Hospital, Boston dDepartment of Leukemia, Memorial Sloan Kettering Cancer Center, New York, NY eDepartment of Internal Medicine, Mayo Clinic,...