Weida Tong

Nov 4, 2024 | nature.com | Ting Li |Xi Chen |Weida Tong

AbstractTranslational research in toxicology has significantly benefited from transcriptomic profiling, particularly in drug safety. However, its application has predominantly focused on limited organs, notably the liver, due to resource constraints. This paper presents TransTox, an innovative AI model using a generative adversarial network (GAN) method to facilitate the bidirectional translation of transcriptomic profiles between the liver and kidney under drug treatment.

Oct 27, 2024 | biorxiv.org | Ting Li |Xi Chen |Weida Tong

AbstractTranslational research in toxicology has significantly benefited from transcriptomic profiling, particularly in drug safety. However, its application has predominantly focused on limited organs, notably the liver, due to resource constraints. This paper presents TransTox, an innovative AI model using a Generative Adversarial Network (GAN) method to facilitate bidirectional translation of transcriptomic profiles between the liver and kidney under drug treatment.

Aug 15, 2024 | nature.com | Binsheng Gong |Jean Thierry-Mieg |Todd Richmond |Rebecca Kusko |Wendell D. Jones |Weida Tong | +1 more

AbstractNext-generation sequencing (NGS) has revolutionized genomic research by enabling high-throughput, cost-effective genome and transcriptome sequencing accelerating personalized medicine for complex diseases, including cancer. Whole genome/transcriptome sequencing (WGS/WTS) provides comprehensive insights, while targeted sequencing is more cost-effective and sensitive.