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3 weeks ago | 
mdpi.com | Ting Li |Feng Liu |Dylan Brown |Nannan Liu
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Nov 30, 2024 | 
pubs.acs.org | Yi-Bo Wang |Wei Liu |Ting Li |Yazhu Lu
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Nov 25, 2024 | 
nature.com | Ting Li |Yuting Ma
AbstractX-linked retinitis pigmentosa (XLRP) is a severe hereditary retinal disorder marked by progressive vision loss due to photoreceptor dysfunction. The retinitis pigmentosa GTPase regulator (RPGR) gene, responsible for most XLRP cases, encodes a protein crucial for the transport of visual signal proteins between the photoreceptor inner and outer segments. However, the mechanism of RPGR mutation causing photoreceptor disorder is not clear and effective treatments remain elusive.
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Nov 4, 2024 | 
nature.com | Ting Li |Xi Chen |Weida Tong
AbstractTranslational research in toxicology has significantly benefited from transcriptomic profiling, particularly in drug safety. However, its application has predominantly focused on limited organs, notably the liver, due to resource constraints. This paper presents TransTox, an innovative AI model using a generative adversarial network (GAN) method to facilitate the bidirectional translation of transcriptomic profiles between the liver and kidney under drug treatment.
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Oct 27, 2024 | 
biorxiv.org | Ting Li |Xi Chen |Weida Tong
AbstractTranslational research in toxicology has significantly benefited from transcriptomic profiling, particularly in drug safety. However, its application has predominantly focused on limited organs, notably the liver, due to resource constraints. This paper presents TransTox, an innovative AI model using a Generative Adversarial Network (GAN) method to facilitate bidirectional translation of transcriptomic profiles between the liver and kidney under drug treatment.
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Oct 9, 2024 | 
pubs.rsc.org | Xiaoqin Cui |Xuehuan Zhang |Ting Li |Sheng Zhu
Substituent Effect in Determining the Total Structure of an All-Alkynyl-Protected Ag98 Nanocluster for Methanol Tolerant Oxygen Reduction Reaction
Metal nanoclusters (NCs) with atomically precise structures are desirable models for truly understanding their structure-property relationship.
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Sep 20, 2024 | 
onlinelibrary.wiley.com | Yunyun Deng |Yiming Yao |Chang Wang |Ting Li
Aims To evaluate the effect of dignity therapy on dignity, anxiety, depression and overall quality of life for people with burns. Design A single-blind, double-arm, parallel randomised controlled study. Methods The Patient Dignity Scale, Hospital Anxiety and Depression Scale, and Burn-Specific Health Scale-Short were employed to assess the dignity, anxiety, depression and overall quality of life for people with burns.
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Aug 30, 2024 | 
cleantechnica.com | Ting Li |Wei Li
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China’s rapid adoption of new energy vehicles is helping to accelerate the global energy transitionEvery summer is a reminder of the urgency of climate change. Last July, the global average temperature rose to a record high. This summer, floods, hurricanes, and extreme high temperatures again ring warning bells about the most imminent and grave threat to humanity.
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Aug 28, 2024 | 
nature.com | Jiantao Chen |Zhijian Yang |Ranran Zhai |Xiao Feng |Ting Li |Denis Maslov | +25 more
AbstractUnderstanding the genetic basis of neuro-related proteins is essential for dissecting the molecular basis of human behavioural traits and the disease aetiology of neuropsychiatric disorders. Here the SCALLOP Consortium conducted a genome-wide association meta-analysis of over 12,000 individuals for 184 neuro-related proteins in human plasma. The analysis identified 125 cis-regulatory protein quantitative trait loci (cis-pQTL) and 164 trans-pQTL.
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May 31, 2024 | 
nature.com | Xiao Feng |Yanjun Zan |Ting Li |Yang Liu
AbstractGenome-wide association study (GWAS) is a powerful tool to identify genomic loci underlying complex traits. However, the application in natural populations comes with challenges, especially power loss due to population stratification. Here, we introduce a bivariate analysis approach to a GWAS dataset of Arabidopsis thaliana. We demonstrate the efficiency of dual-phenotype analysis to uncover hidden genetic loci masked by population structure via a series of simulations.
