Wenjun Li Journalist Profile

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Tissue-resident CCR2+ macrophage TREM-1/3 signaling is necessary for monocyte and neutrophil recruitment to injured hearts

Mar 4, 2025 | cell.com | Yuriko Terada |Wenjun Li |Junedh Amrute |Charles Liu |Andrew Koenig |Hannah P. Luehmann | +15 more

KeywordsmacrophagestransplantationheartTREM-1/3CCR2Research topic(s)CP: ImmunologyIntroductionCardiac transplantation remains the ultimate treatment for patients with end-stage heart disease.1 Myocardial ischemia-reperfusion injury (IRI) is a form of sterile inflammation that is of major clinical significance as it adversely impacts both short- and long-term outcomes.

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