Wentao Xu

3 weeks ago | biorxiv.org | Tao Lin |Chenjun Huang |Chenhao Tong |Wentao Xu

AbstractPhysiologically, hepatocytes perform an estimated 500 essential liver functions to ensure systemic homeostasis. The mechanisms how hepatocytes maintain these numerous crucial functions in response to physiological and pathophysiological challenges are largely unknown. In this study, we found that vital liver function genes (e.g., HNF4A, ALB, coagulation factors, and SLC2A2) in hepatocytes possess super-enhancers.

Jan 15, 2025 | arxiv.org | Wentao Xu