Xiang Qiu

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Human genetic variation shapes the antibody repertoire across B cell development

1 month ago | biorxiv.org | Oscar Rodriguez |Oscar Rodríguez |Óscar Rodríguez |Xiang Qiu |Kaitlyn T Shields |Christopher Dunn

AbstractThe peripheral antibody repertoire is shaped by inherited genetic variation and selection during B cell development. However, how the repertoire changes across developmental stages and the relative impact of genetics and selection in establishing the antibody repertoire remain largely unknown.

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