Xiaoqun Wang

Oct 9, 2024 | mdpi.com | Jijian Lian |Xiaowei Wang |Xiaoqun Wang |Yanjia Chen

1. IntroductionGlobal warming is recognized as a global environmental crisis, and the cause of global warming is excessive carbon emissions. However, social development is inseparable from energy utilization. Presently, the main energy utilization is multi-carbon mineral energy such as oil and coal. Therefore, in order to alleviate the climate warming crisis, low-carbon energy must be used and developed.

Jun 13, 2024 | biorxiv.org | Xiaoqun Wang |Qian Wu |Beijing Normal

AbstractDoublecortin (DCX) is one of the major causal proteins leading to lissencephaly and subcortical band heterotopia in human patients. However, our understanding of this disease, as well as the function of DCX during neurogenesis, remains limited due to the absence of suitable animal models that accurately represent human phenotypes. Here, we conducted a comprehensive examination of the neocortex at different stages in DCX knockout ferrets.

Mar 26, 2024 | mdpi.com | Jijian Lian |Xiaowei Wang |Xiaoqun Wang |Dongke Wu

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Jan 4, 2024 | nature.com | Xiaoqun Wang

AbstractThe spinal cord is a crucial component of the central nervous system that facilitates sensory processing and motor performance. Despite its importance, the spatiotemporal codes underlying human spinal cord development have remained elusive. In this study, we have introduced an image-based single-cell transcription factor (TF) expression decoding spatial transcriptome method (TF-seqFISH) to investigate the spatial expression and regulation of TFs during human spinal cord development.

Nov 21, 2023 | nature.com | Xiaoqun Wang

AbstractHuman cerebellar development is orchestrated by molecular regulatory networks to achieve cytoarchitecture and coordinate motor and cognitive functions. Here, we combined single-cell transcriptomics, spatial transcriptomics and single cell chromatin accessibility states to systematically depict an integrative spatiotemporal landscape of human fetal cerebellar development.