Xin Yi

4 weeks ago | digitalcommons.library.tmc.edu | Madison Kelly |Karan Sharma |Christian Wright |Xin Yi

α2δ1 subunit, mechanotransduction, voltage-sensitive calcium channel, bone formation, loading 10.1093/jbmrpl/ziad008 Post-print Kelly, Madison M; Sharma, Karan; Wright, Christian S; Yi, Xin; Reyes Fernandez, Perla C; Gegg, Aaron T; Gorrell, Taylor A; Noonan, Megan L; Baghdady, Ahmed; Sieger, Jacob A; Dolphin, Annette C; Warden, Stuart J; Deosthale, Padmini; Plotkin, Lilian I; Sankar, Uma; Hum, Julia M; Robling, Alexander G; Farach-Carson, Mary C; and Thompson, William R, "Loss of the...

Dec 17, 2024 | mdpi.com | Xin Yi

3. Results and Discussion 3.1. Wood-Burning Experiment 3.1.1. Heat-Release RateThe heat-release rate (HRR) is an essential metric indicative of fire propagation in historic timber structures. It represents the temporal variation of heat emission at the location of the fire and influences the temperature generated by the blaze [34]. The HRR profiles for FP and 240C are presented in Figure 5.

Nov 27, 2024 | molecularneurodegeneration.biomedcentral.com | Xin Yi |Aik Peng Yong |Brijesh Kumar |Jayne Yi

Human blood was collected from patients from the National Neuroscience Institute of Singapore (NNI), who were recruited for this study with fully informed written consent. All methods and protocols used in this study were performed following the institutional and relevant guidelines and regulations. The clinical diagnosis and pathological features were carefully examined by clinicians and pathologists from NNI. This study was also approved by the Institutional Review Board of NNI (2017/2602).

Aug 29, 2024 | digitalcommons.library.tmc.edu | Madison Kelly |Karan Sharma |Christian Wright |Xin Yi

AbstractVoltage-sensitive calcium channels (VSCCs) influence bone structure and function, including anabolic responses to mechanical loading. While the pore-forming (α1) subunit of VSCCs allows Ca2+ influx, auxiliary subunits regulate the biophysical properties of the pore. The α2δ1 subunit influences gating kinetics of the α1 pore and enables mechanically induced signaling in osteocytes; however, the skeletal function of α2δ1 in vivo remains unknown.

Dec 8, 2023 | mdpi.com | Hua Zhu |Xin Yi |Si-Si Jia |Chun-Yao Liu

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