Yan Dong

Dec 5, 2024 | biorxiv.org | Francesco N Carelli |Alex Appert |Yan Dong |Matthew Hill

AbstractMultimodal single-cell profiling provides a powerful approach for unravelling the gene regulatory mechanisms that drive development, by simultaneously capturing cell-type-specific transcriptional and chromatin states. However, its inherently destructive nature hampers the ability to trace regulatory dynamics between mother and daughter cells.

Nov 30, 2024 | pubs.rsc.org | Li Wang |Ying Zhu |Yan Dong |Jingjing Wang

NiS2 nanoboxes wrapped in carbon with a core-shell structure for high-performance sodium storage One-dimensional nitrogen-doped carbon nanotube wrapped NiS2 core-shell nanoboxes have been developed. The hollow interior and protective carbon layer significantly enhance sodium storage properties, showing high reversible capacities and superior cycling stability at high current densities.

Oct 4, 2024 | bmcgenomics.biomedcentral.com | Shichen Gao |Yadong Wang |Jiajia Wang |Yan Dong

The analysis of single-cell transcriptomic data can markedly enhance our understanding of the pathogenic mechanisms underlying HD. Therefore, we used recently accessible single-cell RNA sequencing data [11], which includes two datasets derived from induced pluripotent stem cells (iPSCs) of (i) unaffected control individuals and (ii) HD patients (Fig. 2, left panel). These iPSCs were differentiated into neuron cultures enriched with medium spiny neurons, the cell type predominantly impacted in HD.

Jun 12, 2024 | nature.com | Yan Dong

AbstractThe precise, simultaneous, and rapid detection of essential biomarkers in human tears is imperative for monitoring both ocular and systemic health. The utilization of a wearable colorimetric biochemical sensor exhibits potential in achieving swift and concurrent detection of pivotal biomarkers in tears. Nevertheless, challenges arise in the collection, interpretation, and sharing of data from the colorimetric sensor, thereby restricting the practical implementation of this technology.

Jul 8, 2023 | aging-us.com | Chao Sun |Kun Wen |Bin Zhang |Yan Dong

Research Paper Volume 15, Issue 13 pp 6380—6399 1 Department of Pharmacy, The Second Hospital of Shandong University, Jinan 250033, China 2 Department of Pharmacy, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan 250021, China 3 Department of Pharmacy, The First Affiliated Hospital of Shandong First Medical University and Shandong Provincial Qianfoshan Hospital, Jinan 250014, China 4 Department of Critical Care Medicine, The Second Hospital of Shandong...