Yashaar Chaichian

Mar 8, 2024 | insight.jci.org | JCI Insight |Kavita Sarin |Hong Zheng |Yashaar Chaichian

AbstractUnderstanding the immune responses to SARS-CoV-2 vaccination is critical to optimizing vaccination strategies for individuals with autoimmune diseases, such as systemic lupus erythematosus (SLE). Here, we comprehensively analyzed innate and adaptive immune responses in 19 patients with SLE receiving a complete 2-dose Pfizer-BioNTech mRNA vaccine (BNT162b2) regimen compared with a control cohort of 56 healthy control (HC) volunteers.