Hong Zheng

3 weeks ago | obgyn.onlinelibrary.wiley.com | Nan Zhang |Hong Zheng |Yunong Gao |Tong Shu

Data Availability Statement The datasets generated and/or analysed in the current study are available from the corresponding author upon reasonable request.

Sep 30, 2024 | nature.com | Ting Hu |Hong Zheng |Yi-Lin Wu |Yi-Ming Wang |Wei Qing Wang |Chen-Wei Huang | +4 more

Depression is a significant mental health issue with extensive economic implications, and recent studies suggest it may be transmitted between individuals. However, the mechanisms of this contagion remain unclear, and the social buffering effect has been understudied. This research employs three rodent models, including stress crossover, cohabitation-induced, and non-contact induced depression contagion models, to explore these mechanisms. Here, we report that that naive mice cohabiting with depressed mice showed increased corticosterone levels and depressive behaviors, unlike those with stressed mice, who did not exhibit these changes and even mitigated desperation in stressed mice. Non-contact cohabitation did not produce significant behavioral differences, but exposure to bedding from depressed mice reduced sucrose preference in naive mice. This study introduces reliable models of depression contagion, suggesting it operates independently of stress transmission. The interplay between depression contagion and social buffering may vary in different contexts. These findings provide new insights into the mechanisms of depression contagion and potential strategies for preventing depressive disorders.

Jul 26, 2024 | link.aps.org | Istanbul Medeniyet |northern Illinois |Hong Zheng |Sevda Sahinbay

Article Text (Subscription Required) Click to ExpandSupplemental Material (Subscription Required) Click to ExpandReferences (Subscription Required) Click to ExpandIssueVol. 110, Iss. 1 — 1 July 2024Access OptionsBuy Article »Log in with individual APS Journal Account »Log in with a username/password provided by your institution »Get access through a U.S. public or high school library »Article part of CHORUSAccepted manuscript will be available starting26 July 2025.

Mar 8, 2024 | insight.jci.org | JCI Insight |Kavita Sarin |Hong Zheng |Yashaar Chaichian

AbstractUnderstanding the immune responses to SARS-CoV-2 vaccination is critical to optimizing vaccination strategies for individuals with autoimmune diseases, such as systemic lupus erythematosus (SLE). Here, we comprehensively analyzed innate and adaptive immune responses in 19 patients with SLE receiving a complete 2-dose Pfizer-BioNTech mRNA vaccine (BNT162b2) regimen compared with a control cohort of 56 healthy control (HC) volunteers.

Dec 14, 2023 | arxiv.org | Wen Wu |Yi Hu |Hong Zheng

[Submitted on 14 Dec 2023 ( v1 ), last revised 24 Dec 2023 (this version, v2)] Title:Metacognition-Enhanced Few-Shot Prompting With Positive Reinforcement Download a PDF of the paper titled Metacognition-Enhanced Few-Shot Prompting With Positive Reinforcement, by Yu Ji and Wen Wu and Yi Hu and Hong Zheng and Liang He Download PDF HTML (experimental) Abstract:Few-shot prompting elicits the remarkable abilities of large language models by equipping them with a few demonstration examples in the...