Yawen Zhao

Oct 22, 2024 | science.org | Teresa Rosenlehner |Jinshan Zhang |Annalisa M. VanHook |Yawen Zhao

Editor’s summaryThe appetite-stimulating hormone ghrelin promotes hepatic lipid accumulation. Zhang et al. investigated the regulation of hepatic lipid homeostasis by Piezo1, a mechanosensitive ion channel that is activated when food ingestion stretches the stomach and that suppresses ghrelin production. Mice lacking Piezo1 in ghrelin-producing cells in the stomach developed hepatic steatosis, which was reversed by pharmacologically blocking the ghrelin receptor.

Jan 30, 2024 | mdpi.com | Yawen Zhao |Nan Ding

This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessArticlebyYawen Zhao 1,† and Nan Ding 2,*,† 1Key Laboratory of Intelligent Control and Optimization for Industrial Equipment, College of Computer Science and Technology, Dalian University of Technology, Liaoning 116000, China2College of Computer Science and Technology, XinJiang Normal University, Urumqi 830010, China*Author to whom correspondence should be addressed.