Yifan Liu

Jan 15, 2025 | nature.com | Yifan Liu

AbstractThe current single-cell analysis technologies such as fluorescence-activated cell sorting (FACS) and fluorescence-activated droplet sorting (FADS) could decipher the cellular heterogeneity but were constrained by low sorting performance and cell viability. Here, an ultra-sensitive single-cell sorting platform has been developed by integrating the FADS technology with Tetramer-HCR-EvaGreen (THE) fluorescence signal amplification.

Dec 4, 2024 | mdpi.com | Fa Zhang |Yang Liu |Zhenhao Cao |Yifan Liu

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Nov 15, 2024 | biorxiv.org | Haicheng Li |Junhua Niu |Yalan Sheng |Yifan Liu

AbstractDNA modifications, such as N6-methyladenine (6mA), play important roles in various processes in eukaryotes. Single molecule, real-time (SMRT) sequencing enables the direct detection of DNA modifications without requiring special sample preparation. However, most SMRT-based studies of 6mA rely on ensemble-level consensus by combining multiple reads covering the same genomic position, which misses the single-molecule heterogeneity.

Nov 15, 2024 | bsssjournals.onlinelibrary.wiley.com | Lingjian Kong |Lin Zhang |Ying Zhang |Yifan Liu

CONFLICT OF INTEREST STATEMENT The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. REFERENCES , , , , , , , , , , , , , , & (2020). The soil-borne identity and microbiome-assisted agriculture: Looking Back to the future. Molecular Plant, 13, 1394–1401. https://doi.org/10.1016/j.molp.2020.09.017 , , , , , , & (2011).

Sep 8, 2024 | arxiv.org | Yifan Liu |Zheng Peng |Hui Lin |Geeta Chandra Raju