Yihong Zhang

Nov 18, 2024 | pubs.rsc.org | Min Zhou |Faheem Muhammad |Jingyuan Zhao |Yihong Zhang

Copper depletion-induced tumor cuproptosis Copper homeostasis is crucial for cells, especially for rapidly proliferating cancerous cells. Copper imbalance-induced cell death (i.e., cuproptosis) has emerged as a new strategy for tumor therapy. While copper accumulation-induced cuproptosis has been extensively investigated and its underlying mechanism recently elaborated, copper depletion-induced cuproptosis remains largely unexplored.

Aug 16, 2024 | mdpi.com | Chen Sun |Yihong Zhang |Shuai Ma

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Jul 16, 2024 | preprints.org | Chen Sun |Yihong Zhang |Shuai Ma

PreprintArticleVersion 1This version is not peer-reviewedVersion 1: Received: 16 July 2024 / Approved: 16 July 2024 / Online: 16 July 2024 (12:57:33 CEST)Sun, C.; Zhang, Y.; Ma, S. DFLM-YOLO: A Lightweight YOLO Model with Multiscale Feature Fusion Capabilities for Open Water Aerial Imagery. Preprints 2024, 2024071302. https://doi.org/10.20944/preprints202407.1302.v1Sun, C.; Zhang, Y.; Ma, S.

Jan 22, 2024 | intpolicydigest.org | Yihong Zhang

In the past year, the European Union has earmarked over $70 billion in a show of unprecedented financial and military support. Yet, as the conflict in Eastern Ukraine grinds into a protracted stalemate, trepidation is brewing within the bloc. EU member states are confronting the hard truths of a strained budget, questioning the long-term feasibility of allocating upwards of €50 billion annually. It’s a fiscal endurance test with geopolitical stakes.

Aug 24, 2023 | mdpi.com | Matthew Helliwell |Yihong Zhang |Aziza El Harchi |Christopher Dempsey

3. Discussion 3.1. Contextualizing the Inhibitory Potency of E-4031-17The potency of E-4031 inhibition of IhERG found in this study is similar to that in prior investigations using mammalian cell line hERG expression [,]. Comparable electrophysiological data for E-4031-17 have not hitherto been reported. Results from [3H]-astemizole binding experiments suggested increased potency of E-4031-17 compared to the parent compound [].