Yingjie Zhu

Sep 4, 2024 | nature.com | Manisha Jalan |Aman Sharma |Xin Pei |Yingjie Zhu |Melody Di Bona |Nadeem Riaz

AbstractCollisions of the transcription and replication machineries on the same DNA strand can pose a significant threat to genomic stability. These collisions occur in part due to the formation of RNA-DNA hybrids termed R-loops, in which a newly transcribed RNA molecule hybridizes with the DNA template strand. This study investigated the role of RAD52, a known DNA repair factor, in preventing collisions by directing R-loop formation and resolution.

Apr 24, 2023 | mdpi.com | Yingjie Zhu |Liying Chen |Chen Wang |Cheng Liu

4. Performance of Composite Girders with Differentiated Connectors in the Service StageTen years after construction, the longitudinal distributions of the deflection, and stresses of the steel top and bottom flanges and the concrete slab are shown in Figure 14. As is shown in Figure 14a, the midspan deflections of the girders in Scheme S and Scheme P were 16% and 4% smaller than those in Scheme U, respectively. The stress of the steel bottom flange in the three schemes was essentially the same.