Youngbin Kim

Jan 2, 2025 | jci.org | Bryan Wang |Seong Won Kim |Lori Luo |Xiaokan Zhang |Rajesh Kumar Soni |Roberta Lock | +11 more

AbstractLoss of Bcl2-associated athanogene 3 (BAG3) is associated with dilated cardiomyopathy (DCM). BAG3 regulates sarcomere protein turnover in cardiomyocytes; however, the function of BAG3 in other cardiac cell types is understudied. In this study, we used an isogenic pair of BAG3-knockout and wild-type human induced pluripotent stem cells (hiPSCs) to interrogate the role of BAG3 in hiPSC-derived cardiac fibroblasts (CFs).

Nov 13, 2024 | onlinelibrary.wiley.com | Daniel Naveed Tavakol |Trevor Nash |Youngbin Kim |Pamela L. Graney

Graphical Abstract Human Organ-on-Chip Platform This cover displays an astronaut holding an organ-on-a-chip model of heart, liver, and bone marrow tissues linked by vascular flow. This graphical representation illustrates the capability of organ-on-achip models to conduct individualized studies of the effects of space stressors on human/astronaut health. More details can be found in article number 2401415 by Daniel Naveed Tavakol, Gordana Vunjak-Novakovic, and co-workers.

Oct 30, 2024 | databricks.com | Ahmed Bilal |Youngbin Kim |Ankit Mathur |Kasey Uhlenhuth

When serving machine learning models, the latency between requesting a prediction and receiving a response is one of the most critical metrics for the end user. Latency includes the time a request takes to reach the endpoint, be processed by the model, and then return to the user. Serving models to users that are based in a different region can significantly increase both the request and response times.

Oct 22, 2024 | databricks.com | Ahmed Bilal |Youngbin Kim |Ankit Mathur |Daniel King

Over the years, organizations have amassed a vast amount of unstructured text data—documents, reports, and emails—but extracting meaningful insights has remained a challenge. Large Language Models (LLMs) now offer a scalable way to analyze this data, with batch inference as the most efficient solution. However, many tools still focus on online inference, leaving a gap for better batch processing capabilities.

Aug 14, 2024 | nature.com | Trevor Nash |Pamela L. Graney |Youngbin Kim |Jonathan Seidman

AbstractSystemic lupus erythematosus (SLE) is a heterogenous autoimmune disease that affects multiple organs, including the heart. The mechanisms of myocardial injury in SLE remain poorly understood. In this study, we engineered human cardiac tissues and cultured them with IgG from patients with SLE, with and without myocardial involvement.