Yu-Hsi Lin

Jun 26, 2024 | digitalcommons.library.tmc.edu | Victoria Yan |Yasaman Barekatain |Yu-Hsi Lin |Nikunj Satani

Metabolically labile prodrugs can experience stark differences in catabolism incurred by the chosen route of administration. This is especially true for phosph(on)ate prodrugs, in which successive promoiety removal transforms a lipophilic molecule into increasingly polar compounds.