Yu-Mei Chang

Sep 8, 2023 | equimanagement.com | Edward Knowles |Patricia Harris |Jonathan Elliott |Yu-Mei Chang

Serum insulin concentration at 60 min (InsulinT60) during an oral sugar test (OST) indicates future laminitis risk and insulin dysregulation (ID). Associations between InsulinT60 and physical and owner-reported variables may help clinicians select individual ponies for ID testing. Associations between InsulinT60 and other metabolic markers may help elucidate ID pathophysiology.

Aug 22, 2023 | beva.onlinelibrary.wiley.com | Edward Knowles |Patricia Harris |Jonathan Elliott |Yu-Mei Chang

1 INTRODUCTION Equine insulin dysregulation (ID) manifests in three forms, namely hyperinsulinaemia, an excessive insulin response to oral sugar/starch and peripheral (tissue) insulin resistance.1 For clinical diagnosis of ID, dynamic tests such as the oral sugar test (OST) are considered to be more sensitive indicators of ID than basal hyperinsulinaemia.1 An association between ID and laminitis is well established.1 Previously we demonstrated that serum insulin concentrations measured in the...