Yuanxin Qiu

Oct 7, 2024 | biorxiv.org | Tingting Wu |Matthew King |Yuanxin Qiu |Mina S. Farag

AbstractBiomolecular condensates are viscoelastic materials. Simulations predict that fluid-like condensations are defined by spatially inhomogeneous organization of the underlying molecules. Here, we test these predictions using single-fluorogen tracking and super-resolution imaging.

Aug 19, 2024 | biorxiv.org | Nadia Aicha Erkamp |Mina S. Farag |Yuanxin Qiu |Daoyuan Qian

AbstractBiomolecular condensates form via macromolecular phase separation, giving rise to coexisting phases delineated by interfaces. Here, we characterize the structures of interfaces formed by phase separation driven by heterotypic interactions in ternary mixtures of two types of RNA molecules and polyethylene glycol. We find that purine-rich RNAs are scaffolds that drive phase separation via strong heterotypic interactions.