Yuchen Zhou

Feb 9, 2024 | mdpi.com | Bo Xu |Zhongke Feng |Yuan Chen |Yuchen Zhou

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Jan 12, 2024 | pubs.rsc.org | Yuchen Zhou |Molecular Biosciences |Ras Baizureen Roseli |Natasha L. Hungerford

Binding of the plant-derived toxin simplexin to bovine protein kinase C: insights from molecular dynamics† Pimelea poisoning of cattle is toxicologically linked to the activation of bovine protein kinase C (PKC) by the plant-derived toxin simplexin. To understand the affinity of PKC for simplexin, we performed molecular dynamics (MD) studies of simplexin, simplexin analogues, and several other activators of PKC.

Oct 18, 2023 | mdpi.com | Jie Li |Yuchen Zhou |Kun Liu |Yifan Wang

2. Results and DiscussionHere, we studied a new-type 2D iodine structure, which is under a high pressure of 15 GPa (see Figure 1). Just as Li et al. reported, the pressure would make iodine atoms more clustered together, so that 2D iodine shows much shorter atomic distances of less than 3 Å and no band gap under the pressure of 15 GPa, different to the general condition [39]. However, iodine is a 2D layered molecular crystal with covalent intramolecular bonds, so atoms are regularly bonded in pairs.