Yulian Tan

Dec 9, 2024 | biorxiv.org | Ting Hu |Yifan Kong |Yulian Tan |Pengcheng Ma

AbstractNeocortex expansion has a concerted relationship with folding, underlying evolution of human cognitive functions. However, molecular mechanisms underlying this significant evolutionary process remains unknown. Here, using tree shrew as an outgroup of primates, we identify a new regulator CCNB1IP1, which acquired its expression before the emergence of primates.

Nov 5, 2024 | biorxiv.org | Jianhong Wang |Yifan Kong |Yulian Tan |Xuezhuang Li

AbstractDNA fork speed, the rate of replication fork progression, has emerged as a cellular plasticity regulator, however, for its role in neurogenesis has never been explored before. Here, we show that fork speed was increased as neural progenitors-radial glial cells (RGCs) transition from symmetric to asymmetric divisions.