Yulin Li

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Articles

StrucTexTv3: An Efficient Vision-Language Model for Text-rich Image Perception, Comprehension, and Beyond

May 31, 2024 | arxiv.org | Yulin Li |Hao Zhou |Weihong Ma |Xingyu Wan
Nuclear to cytoplasmic transport is a druggable dependency in MYC-driven hepatocellular carcinoma - Nature Communications

Jan 31, 2024 | nature.com | Anja Deutzmann |Delaney Sullivan |Renumathy Dhanasekaran |Wei Li |Angela N. Koehler |Yulin Li

AbstractThe MYC oncogene is often dysregulated in human cancer, including hepatocellular carcinoma (HCC). MYC is considered undruggable to date. Here, we comprehensively identify genes essential for survival of MYChigh but not MYClow cells by a CRISPR/Cas9 genome-wide screen in a MYC-conditional HCC model. Our screen uncovers novel MYC synthetic lethal (MYC-SL) interactions and identifies most MYC-SL genes described previously.

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