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  • Nov 14, 2023 | onlinelibrary.wiley.com | Zaira Aversa |Thomas White |Amanda A. Heeren |Cassondra A. Hulshizer

    AL ad libitum BMI body mass index CALERIETM Comprehensive Assessment of Long-term Effects of Reducing Intake of Energy CR calorie restriction GBM gradient boosting machine learning GSEA gene set enrichment analysis HOMA-IR homeostatic model assessment of insulin resistance ITT intention-to-treat NES normalized enrichment score RMR resting metabolic rate SASP senescence-associated secretory phenotype 1 INTRODUCTION Compelling evidence from a wide range of animal studies suggests that calorie...

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