Zhiguo Zhang

Jan 16, 2025 | cell.com | Zhiming Li |Zhiguo Zhang

KeywordsDNA replicationstrand-specific sequencingepigenetic inheritanceparental histone transfernucleosome assemblyDNA damage repairgenome maintenanceIntroductionDNA replication is essential to all living organisms and entails a highly orchestrated process, ensuring the faithful transmission of genetic information from one generation to the next.

Jan 15, 2025 | cell.com | Yimin Shang |Haowen Shi |Minzhi Liu |Deyu Li |Xiaomeng Liu |Minyang Wang | +3 more

Keywordssynthetic biologynitrogenasenitrogen fixation genetransgenic riceprotein instabilityGet full text accessLog in, subscribe or purchase for full access. References1. Zhang, X. ... Managing nitrogen for sustainable developmentNature. 2015; 528:51-592. Curatti, L. ∙ Rubio, L.M.Challenges to develop nitrogen-fixing cereals by direct nif-gene transferPlant Sci. 2014; 225:130-1373. Oldroyd, G.E. ∙ Dixon, R. Biotechnological solutions to the nitrogen problemCurr. Opin. Biotechnol. 2014; 26:19-244.

Aug 25, 2024 | mdpi.com | Zhiguo Zhang |Haoran Li

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Mar 28, 2024 | mdpi.com | Zhiguo Zhang |Baowen Zhang |Xing LI |Shenghu Ding

All articles published by MDPI are made immediately available worldwide under an open access license. No specialpermission is required to reuse all or part of the article published by MDPI, including figures and tables. Forarticles published under an open access Creative Common CC BY license, any part of the article may be reused withoutpermission provided that the original article is clearly cited. For more information, please refer tohttps://www.mdpi.com/openaccess.

Mar 20, 2024 | nature.com | Zhiming Li |Zhiguo Zhang |Xuejun Jiang |Brent R. Stockwell

AbstractYEATS domain-containing protein GAS41 is a histone reader and oncogene. Here, through genome-wide CRISPR-Cas9 screenings, we identify GAS41 as a repressor of ferroptosis. GAS41 interacts with NRF2 and is critical for NRF2 to activate its targets such as SLC7A11 for modulating ferroptosis. By recognizing the H3K27-acetylation (H3K27-ac) marker, GAS41 is recruited to the SLC7A11 promoter, independent of NRF2 binding.