Zhiguo Zou

Jul 16, 2024 | biorxiv.org | Xiyuan Lu |Yifan Wang |Zhiguo Zou |Shanghai Jiaotong

AbstractThe authors have withdrawn their manuscript owing to further revisions and additional experiments are needed to ensure the accuracy and completeness of the research findings. As a result, we believe it is in the best interest of the scientific community and the integrity of the manuscript to withdraw it at this time.

Oct 20, 2023 | biorxiv.org | Xiyuan Lu |Yifan Wang |Shanghai Jiaotong |Zhiguo Zou

AbstractRATIONALE: Preeclampsia (PE) is a hypertensive disorder that occurs during pregnancy and is characterized by failed spiral artery remodeling. Calcium deficiency in women has been strongly linked to an increased risk of developing PE. Mitochondrial calcium ([Ca2+]m) homeostasis is essential to regulate vascular smooth muscle cell (VSMC) function. However, the role of [Ca2+]m in PE development remains largely unknown.