Agaz Wani

Dec 18, 2024 | genomemedicine.biomedcentral.com | Seyma Katrinli |Agaz Wani |Adam X. Maihofer |Andrew Ratanatharathorn |Nikolaos P. Daskalakis |Janitza L. Montalvo-Ortiz | +7 more

The study includes 2156 current PTSD cases and 2921 trauma-exposed controls from 9 civilian cohorts: BEAR, DNHS, DCHS, GTP, NIU, Shared Roots, AURORA, H3A_Rwanda, WTC; and 9 military cohorts: GMRFQUT, MRS, PRISMO, Army STARRS, PROGrESS, NCPTSD/TRACTS, INTRuST, and VA cohorts (VA-M-AA and VA-M-EA). For DNHS, GTP, MRS, PRISMO, and Army STARRS, two different datasets were available based on the DNAm array.

Jul 15, 2024 | medrxiv.org | Seyma Katrinli |Agaz Wani |Adam X. Maihofer |Andrew Ratanatharathorn

CYC is an employee of Biogen. NPD has served on scientific advisory boards for BioVie Pharma, Circular Genomics and Sentio Solutions for unrelated work. NRN serves as an unpaid member of the Ilumivu advisory board. SAMR receives support from the Wounded Warrior Project (WWP), Department of Veterans Affairs (VA), National Institute of Health (NIH), McCormick Foundation, Tonix Pharmaceuticals, Woodruff Foundation, and Department of Defense (DOD).

Feb 8, 2024 | biologicalpsychiatryjournal.com | Seyma Katrinli |Agaz Wani |Xiang Zhao |Adam X. Maihofer

The link between posttraumatic stress disorder (PTSD) and the immune system is supported by multiple studies that identified DNA methylation (DNAm) differences in immune-related genes in PTSD, as well as changes in cell composition in those with PTSD. Here, we present the results of the largest cell type-specific epigenome-wide association study (EWAS) of PTSD to date.