Aimee Axelrod Parker

Apr 29, 2024 | microbiologyresearch.org | Steve James |Aimee Axelrod Parker |Catherine Purse |Dave Baker

The cynomolgus macaque Macaca fascicularis is a non-human primate (NHP) widely used in biomedical research as it shares behavioural genetic immunological and physiological similarities with humans. These similarities may extend to the enteric microbiome with some microbial taxa common to both humans and NHPs. However to date the majority of these microbial surveys have focused on the prokaryome and have largely ignored or overlooked the NHP gut mycobiome.

Oct 6, 2023 | frontiersin.org | Kristy A Nielson |Aimee Axelrod Parker |Brett M. Frye

1. IntroductionAlzheimer’s disease (AD) is the most common form of dementia, leading to a globally heavy healthcare and economic burden (Jia et al., 2018, 2020). According to the National Institute on Aging and Alzheimer’s Association (NIA-AA) research framework, AD-related biomarkers are mainly classified into three existing groups, including amyloid-β (Aβ) deposition, pathologic tau aggregation, and neurodegeneration [AT(N)] (Jack et al., 2018; Scheltens et al., 2021).