Kristy A Nielson

Oct 10, 2023 | frontiersin.org | Perioperative Medicine |Kristy A Nielson

With the development of technology, more and more infants are undergoing general anesthesia for surgery, other interventions, or clinical examinations in the early stages of life. However, whether general anesthesia affects the function and structure of the developing infant brain remains an important, complex, and controversial issue. Sevoflurane is the most commonly used anesthetic for infants, but this drug has potential neurotoxicity.

Oct 6, 2023 | frontiersin.org | Kristy A Nielson |Aimee Axelrod Parker |Brett M. Frye

1. IntroductionAlzheimer’s disease (AD) is the most common form of dementia, leading to a globally heavy healthcare and economic burden (Jia et al., 2018, 2020). According to the National Institute on Aging and Alzheimer’s Association (NIA-AA) research framework, AD-related biomarkers are mainly classified into three existing groups, including amyloid-β (Aβ) deposition, pathologic tau aggregation, and neurodegeneration [AT(N)] (Jack et al., 2018; Scheltens et al., 2021).

Jul 19, 2023 | frontiersin.org | Kristy A Nielson

As advanced age affects body organs and systems, older people are more vulnerable to neurological conditions or disorders. This Research Topic has collected articles that provide opinions and perspectives related to the field of neural rehabilitation for the elderly, particularly on aspects such as neuromotor function, rehabilitation, and exercise. With aging, older adults experience significant declines in cognitive function. Tao et al.

Jun 13, 2023 | frontiersin.org | Kristy A Nielson

With population aging, tactics to promote healthy aging and counteract the progress of age-related neurodegenerative diseases have become more and more important. A balanced and nutritious diet is vital for keeping fit, especially as age increases. The brain has a high requirement for nutrition, and nutritional imbalance can inhibit its structural and functional integrity, seriously affecting cognitive functioning (Dienel, 2019).

May 30, 2023 | frontiersin.org | Shanghai Jiao Tong |Kristy A Nielson |Vinod Kumar |Xia Shen

IntroductionUnder normal physiological conditions, the human brain requires 20% of the cardiac output and consumes 20% of the body’s oxygen and glucose (Iadecola, 2013). Since the brain stores little energy, it obtains energy through its blood supply, which must pass through the blood–brain barrier (BBB; Iadecola, 2017). The BBB is an important structure that maintains the homeostasis of the brain’s internal environment and protects the physiological functions of the central nervous system.