Ali Abbara

1 month ago | onlinelibrary.wiley.com | Yasir S. Elhassan |James M Hawley |Leanne Cussen |Ali Abbara

1 Introduction and Methodology Androgen excess is defined as clinical or biochemical evidence of increased production of androgenic steroids in women. It is observed in up to 10% of women of reproductive age and less commonly in postmenopausal women [1]. Androgen excess typically manifests clinically as hirsutism or acne, but more severe and prolonged exposure can lead to overt virilisation, including clitoromegaly, deepening of the voice, female pattern hair-loss (FPHL) or erythrocytosis [2].

Feb 19, 2025 | endocrine-abstracts.org | Bijal Patel |Ali Abbara |Arthur Yeung |Maria Phylactou

SFEBES2025 Oral Communications Reproductive and Neuroendocrinology (6 abstracts) Kisspeptin: a novel tool to interrogate hypothalamic function in women presenting with menstrual disturbance

Aug 18, 2024 | onlinelibrary.wiley.com | Hugo Walford |Ali Abbara |Sophie Clarke |Bede Tyler

1 INTRODUCTION Polycystic ovary syndrome (PCOS) is a lifelong reproductive, endocrine, and metabolic disorder that affects 15% of women of reproductive age and characterised by ovulatory dysfunction, hyperandrogenism, and polycystic ovary morphology.1 PCOS is a multisystemic syndrome with a varied clinical presentation and several phenotypes.

Aug 1, 2024 | jci.org | Ali Abbara |Waljit S. Dhillo |Encarnacion Torres |Manuel Tena-Sempere

AbstractKisspeptin is an essential neuropeptide sitting at the apex of the hypothalamo-pituitary-gonadal (HPG) endocrine axis to regulate gonadotropin-releasing hormone (GnRH) neurons and downstream reproductive hormones. Kisspeptin neurons integrate feedback from sex steroids facilitating regulation of the menstrual cycle and mediate the effects of metabolic stressors on the reproductive axis.

Feb 29, 2024 | journals.plos.org | Margaritis Voliotis |Ali Abbara |Julia K Prague |Macleod Diabetes

Loading metrics Open Access Peer-reviewedResearch Article ? This is an uncorrected proof. Citation: Voliotis M, Abbara A, Prague JK, Veldhuis JD, Dhillo WS, Tsaneva-Atanasova K (2024) HormoneBayes: A novel Bayesian framework for the analysis of pulsatile hormone dynamics. PLoS Comput Biol 20(2): e1011928. https://doi.org/10.1371/journal.pcbi.1011928Editor: Marc R.