Ali Abbara

Feb 19, 2025 | endocrine-abstracts.org | Bijal Patel |Ali Abbara |Arthur Yeung |Maria Phylactou

SFEBES2025 Oral Communications Reproductive and Neuroendocrinology (6 abstracts) Kisspeptin: a novel tool to interrogate hypothalamic function in women presenting with menstrual disturbance

Aug 18, 2024 | onlinelibrary.wiley.com | Hugo Walford |Ali Abbara |Sophie Clarke |Bede Tyler

1 INTRODUCTION Polycystic ovary syndrome (PCOS) is a lifelong reproductive, endocrine, and metabolic disorder that affects 15% of women of reproductive age and characterised by ovulatory dysfunction, hyperandrogenism, and polycystic ovary morphology.1 PCOS is a multisystemic syndrome with a varied clinical presentation and several phenotypes.

Aug 1, 2024 | jci.org | Ali Abbara |Waljit S. Dhillo |Encarnacion Torres |Manuel Tena-Sempere

AbstractKisspeptin is an essential neuropeptide sitting at the apex of the hypothalamo-pituitary-gonadal (HPG) endocrine axis to regulate gonadotropin-releasing hormone (GnRH) neurons and downstream reproductive hormones. Kisspeptin neurons integrate feedback from sex steroids facilitating regulation of the menstrual cycle and mediate the effects of metabolic stressors on the reproductive axis.

Feb 29, 2024 | journals.plos.org | Margaritis Voliotis |Ali Abbara |Julia K Prague |Macleod Diabetes

Loading metrics Open Access Peer-reviewedResearch Article ? This is an uncorrected proof. Citation: Voliotis M, Abbara A, Prague JK, Veldhuis JD, Dhillo WS, Tsaneva-Atanasova K (2024) HormoneBayes: A novel Bayesian framework for the analysis of pulsatile hormone dynamics. PLoS Comput Biol 20(2): e1011928. https://doi.org/10.1371/journal.pcbi.1011928Editor: Marc R.

Feb 29, 2024 | onlinelibrary.wiley.com | Jhia Jiat Teh |Sophie Clarke |Ali Abbara |Rachel Morman

1 INTRODUCTION Polycystic ovary syndrome (PCOS) is a chronic lifelong condition affecting up to 20% of women worldwide with serious implications for their general health and wellbeing.1 It is the commonest endocrine disorder affecting women of childbearing age, with characteristic symptoms, signs and associated risk factors including irregular periods, anovulation, acne, hirsutism and obesity.2 PCOS manifestations vary across different populations influenced by genetic susceptibility leading...