Amy C. Justice

Nov 4, 2024 | jamanetwork.com | Vincent Lo Re |Jessie Torgersen |Amy C. Justice |Alyssa K. Mezochow

Risk of Liver Injury With Potentially Hepatotoxic Drugs—Reply Severe Acute Liver Injury After Hepatotoxic Medication Initiation Jessie Torgersen, MD, MHS, MSCE; Alyssa K. Mezochow, MD; Craig W. Newcomb, MS; Dean M. Carbonari, MS; Sean Hennessy, PharmD, PhD; Christopher T. Rentsch, PhD; Lesley S. Park, PhD; Janet P. Tate, ScD; Norbert Bräu, MD; Debika Bhattacharya, MD; Joseph K. Lim, MD; Catherine Mezzacappa, MD; Basile Njei, MD, PhD; Jason A. Roy, PhD; Tamar H.

Apr 16, 2024 | nature.com | Sylvanus Toikumo |Benjamin Pham |Travis T. Mallard |John J Meredith |Laura Vilar-Ribó |Emma Johnson | +14 more

AbstractTobacco use disorder (TUD) is the most prevalent substance use disorder in the world. Genetic factors influence smoking behaviours and although strides have been made using genome-wide association studies to identify risk variants, most variants identified have been for nicotine consumption, rather than TUD.

Jan 24, 2024 | medicalxpress.com | Amy C. Justice |Julie Parry

According to the Centers for Disease Control and Prevention, cancer is a leading cause of death in the United States. Unfortunately for American men, prostate cancer remains one of the deadliest cancers. Early diagnosis and treatment are essential to decrease cancer mortality; however, for many common types of cancer, including prostate, breast, thyroid, and cervical cancer, overtreatment is a growing concern.

Jan 23, 2024 | medicine.yale.edu | Amy C. Justice |Julie Parry |New Tool"

by Amy Justice and Julie ParryAccording to the Centers for Disease Control and Prevention, cancer is a leading cause of death in the United States. Unfortunately for American men, prostate cancer remains one of the deadliest cancers. Early diagnosis and treatment are essential to decrease cancer mortality; however, for many common types of cancer, including prostate, breast, thyroid, and cervical cancer, overtreatment is a growing concern.

Dec 7, 2023 | nature.com | Hang Zhou |Rachel L. Kember |Joseph D. Deak |Travis T. Mallard |Jiayi Xu |Emma Johnson | +18 more

AbstractProblematic alcohol use (PAU), a trait that combines alcohol use disorder and alcohol-related problems assessed with a questionnaire, is a leading cause of death and morbidity worldwide. Here we conducted a large cross-ancestry meta-analysis of PAU in 1,079,947 individuals (European, N = 903,147; African, N = 122,571; Latin American, N = 38,962; East Asian, N = 13,551; and South Asian, N = 1,716 ancestries).