Amy Chung

1 month ago | nature.com | Chau Huy Quang |Ian Frazer |Bruce D. Wines |Amy Chung |Zheng Quan Toh

AbstractThe WHO has given a permissive recommendation for an off-label one-dose human papillomavirus (HPV) vaccine schedule to prevent cervical cancer, based on evidence of comparable protection to two or three doses of vaccine. While neutralizing antibodies are thought to be the primary mechanism of protection, the persistence of immunity and whether other antibody-mediated mechanisms of protection are involved is unclear.

Sep 19, 2024 | nature.com | Janice Z. Jia |Haogao Gu |Raghavan Varadarajan |Nisha Bhandari |Malik Peiris |Gabriel M Leung | +3 more

Correction to: Nature Communications https://doi.org/10.1038/s41467-024-47590-0, published online 13 April 2024The original version of this Article contained an error in the final paragraph of page 5, second to last sentence in that it contained incorrect p-values for Figure 3 panel d (p-value changed from p = 0.0427 to p = 0.0373) and panel e (p-value changed from p = 0.0017 to p = 0.0034).

Jul 16, 2024 | nature.com | Thomas S. Fulford |Marc Rigau |Amy Chung |Michael Parker |Andreas Behren |Nicholas A. Gherardin | +1 more

AbstractButyrophilin (BTN) molecules are emerging as key regulators of T cell immunity; however, how they trigger cell-mediated responses is poorly understood. Here, the crystal structure of a gamma-delta T cell antigen receptor (γδTCR) in complex with BTN2A1 revealed that BTN2A1 engages the side of the γδTCR, leaving the apical TCR surface bioavailable. We reveal that a second γδTCR ligand co-engages γδTCR via binding to this accessible apical surface in a BTN3A1-dependent manner.

Jun 14, 2024 | onlinelibrary.wiley.com | Chau Huy Quang |Amy Chung |Troy J Kemp |Tupou Ratu

1 INTRODUCTION Human papillomavirus (HPV) vaccines are highly effective at preventing vaccine-type HPV infections and cervical cancer precursors.

May 30, 2024 | lexology.com | Amy Chung

The Olympic Games started in Ancient Greece nearly 3,000 years ago and is now the world’s greatest sporting competition. According to a study by the Centre for Law and Economics of Sport commissioned by the organising committee, the Paris 2024 Olympic Games are expected to generate up to €11.5bn in economic gain for the Paris region.